Shanzhiside methyl ester( —— )

Catalog No. M18948 CAS No. 64421-28-9

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Datasheet

HNMR

HPLC

MSDS

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Product Name

Shanzhiside methyl ester
Note

Research use only, not for human use.
Brief Description

Shanzhiside methylester reduces neuropathic pain by activating spinal GLP-1 receptors and subsequently stimulating microglial β-endorphin expression via the p38 MAPK signaling.
Description

Shanzhiside methylester reduces neuropathic pain by activating spinal GLP-1 receptors and subsequently stimulating microglial β-endorphin expression via the p38 MAPK signaling.
In Vitro

——
In Vivo

Shanzhiside methyl ester exerts dose-dependent and long-lasting (>4 h) anti-allodynic effects in spinal nerve injury-induced neuropathic rats, with a maximal inhibition of 49% and a projected ED50 of 40.4 μg.
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

GLP-1
Research Area

——
Indication

——

CAS Number

64421-28-9
Formula Weight

406.38
Molecular Formula

C17H26O11
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (246.08 mM)
SMILES

[C@@H]1([C@H]2[C@@H](C(=CO1)C(=O)OC)[C@@H](C[C@]2(C)O)O)O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO
Chemical Name

——

1. Fan PC,et al. Biomed Chromatogr. 2012 Dec;26(12):1543-51.

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